NTRK1 polyclonal antibody
产品名称： NTRK1 polyclonal antibody
英文名称： NTRK1 polyclonal antibody
产品编号： PAB3399
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NTRK1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NTRK1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of NTRK1 polyclonal antibody (Cat # PAB3399) in mouse kidney tissue lysates (35 ug/lane). TRKA (arrow) was detected using the purified polyclonal antibody.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with NTRK1 polyclonal antibody (Cat # PAB3399) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Entrez GeneID:
- 4914
- Protein Accession#:
- NP_002520;P04629
- Gene Name:
- NTRK1
- Gene Alias:
- DKFZp781I14186,MTC,TRK,TRK1,TRKA,p140-TrkA
- Gene Description:
- neurotrophic tyrosine kinase, receptor, type 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
- Other Designations:
- OTTHUMP00000038736,Oncogene TRK,high affinity nerve growth factor receptor,tyrosine kinase receptor A
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Asperger Syndrome
- Autistic Disorder
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Eating Disorders
- Edema
- Genetic Predisposition to Disease
- Hereditary Sensory and Autonomic Neuropathies
- Hyperparathyroidism, Secondary
- Kidney Failure, Chronic
- Leukemia, Myeloid, Acute
- Mental Disorders
- Neuroblastoma
- Social Perception
- Thyroid Diseases
- Thyroid Neoplasms