UGT1A6 monoclonal antibody (M03), clone 4A10
产品名称: UGT1A6 monoclonal antibody (M03), clone 4A10
英文名称: UGT1A6 monoclonal antibody (M03), clone 4A10
产品编号: H00054578-M03
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant UGT1A6.
- Immunogen:
- UGT1A6 (NP_001063, 44 a.a. ~ 143 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESK
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged UGT1A6 is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 54578
- GeneBank Accession#:
- NM_001072
- Protein Accession#:
- NP_001063
- Gene Name:
- UGT1A6
- Gene Alias:
- GNT1,HLUGP,HLUGP1,MGC29860,UDPGT,UGT1,UGT1A6S,UGT1F
- Gene Description:
- UDP glucuronosyltransferase 1 family, polypeptide A6
- Omim ID:
- 606431
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000065199,UDP glycosyltransferase 1 family, polypeptide A6,UDP-glucuronosyltransferase 1 family polypeptide A6s,UDP-glucuronosyltransferase 1A6,phenol-metabolizing UDP-glucuronosyltransferase
- Gene Pathway
- Androgen and estrogen metabolism
- Ascorbate and aldarate metabolism
- Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes
- Metabolic pathways
- Metabolism of xenobiotics by cytochrome P450
- Pentose and glucuronate interconversions
- Porphyrin and chlorophyll metabolism
- Retinol metabolism
- Starch and sucrose metabolism
- Related Disease