CDA Pre-design Chimera RNAi
产品名称： CDA Pre-design Chimera RNAi
英文名称： CDA Pre-design Chimera RNAi
产品编号： H00000978-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens cytidine deaminase (CDA), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001785
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 978
- Gene Name:
- CDA
- Gene Alias:
- CDD
- Gene Description:
- cytidine deaminase
- Omim ID:
- 123920
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002883,cytidine aminohydrolase,cytosine nucleoside deaminase,small cytidine deaminase
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Pancreatic Ductal
- Colorectal Neoplasms
- Disease Progression
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hearing Loss
- Kidney Failure, Chronic
- Leukemia
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Neoplasm Recurrence, Local
- Neoplasms
- Pancreatic Neoplasms
- Recurrence
- Stomach Neoplasms