REL polyclonal antibody
产品名称： REL polyclonal antibody
英文名称： REL polyclonal antibody
产品编号： PAB4431
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of REL.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human REL.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation.
Jain A, Ma CA, Lopez-Granados E, Means G, Brady W, Orange JS, Liu S, Holland S, Derry JM.J Clin Invest. 2004 Dec;114(11):1593-602.
- 2.
- Differential expression patterns of c-REL protein in classic and nodular lymphocyte predominant Hodgkin lymphoma.
Xiao Q, Shen N, Hedvat CV, Moskowitz CH, Sussman LK, Filippa DA, Zelenetz AD, Houldsworth J, Chaganti RS, Teruya-Feldstein J.Appl Immunohistochem Mol Morphol. 2004 Sep;12(3):211-5.
- 3.
- Relationship between REL amplification, REL function, and clinical and biologic features in diffuse large B-cell lymphomas.
Houldsworth J, Olshen AB, Cattoretti G, Donnelly GB, Teruya-Feldstein J, Qin J, Palanisamy N, Shen Y, Dyomina K, Petlakh M, Pan Q, Zelenetz AD, Dalla-Favera R, Chaganti RS.Blood. 2004 Mar 1;103(5):1862-8. Epub 2003 Nov 13.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of REL polyclonal antibody (Cat # PAB4431) in HeLa cell line lysate . REL (arrow) was detected using the purified REL polyclonal antibody (Cat # PAB4431) .
- Entrez GeneID:
- 5966
- Protein Accession#:
- NP_002899;Q04864
- Gene Name:
- REL
- Gene Alias:
- C-Rel
- Gene Description:
- v-rel reticuloendotheliosis viral oncogene homolog (avian)
- Omim ID:
- 164910
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM
- Other Designations:
- C-Rel proto-oncogene protein,oncogene REL, avian reticuloendotheliosis,v-rel avian reticuloendotheliosis viral oncogene homolog,v-rel reticuloendotheliosis viral oncogene homolog
- Related Disease
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Celiac Disease
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Myeloma
- Occupational Diseases
- Psoriasis
- Waldenstrom Macroglobulinemia
- Werner syndrome