IFNG monoclonal antibody
产品名称： IFNG monoclonal antibody
英文名称： IFNG monoclonal antibody
产品编号： MAB5422
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against full length recombinant IFNG.
- Immunogen:
- Recombinant protein corresponding to full length human IFNG.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- The IFN-gamma antibody reacts with human recombinant protein in ELISA and Western Blot at various concentrations. Additionally, in direct ELISA, this antibody shows no cross-reactivity with other cytokines tested. Molecular Weight of IFN-gamma: 20-25KDa.
- Form:
- Liquid
- Storage Buffer:
- In PBS
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000-1:20000)
Western Blot (1-2 ug/mL)
Immunofluorescence (1:100-1:500)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes.
Halfter UM, Derbyshire ZE, Vaillancourt RR.Biochem J. 2005 May 15;388(Pt 1):17-28.
- 2.
- Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.
Sizemore N, Agarwal A, Das K, Lerner N, Sulak M, Rani S, Ransohoff R, Shultz D, Stark GR.Proc Natl Acad Sci U S A. 2004 May 25;101(21):7994-8. Epub 2004 May 17.
- 3.
- Interferon-gamma activation of polymorphonuclear neutrophil function.
Ellis TN, Beaman BL.Immunology. 2004 May;112(1):2-12.
- Application Image
- Western Blot
- Immunofluorescence
- ELISA
- Entrez GeneID:
- 3458
- Protein Accession#:
- NM_000619
- Gene Name:
- IFNG
- Gene Alias:
- IFG,IFI
- Gene Description:
- interferon, gamma
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Interferon-gamma (IFNG), or type II interferon, is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNG in the immune system stems in part from its ability to inhibit viral replication directly, but most importantly derives from its immunostimulatory and immunomodulatory effects. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 (MIM 186940) and CD8 (see MIM 186910) cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops (Schoenborn and Wilson, 2007 [PubMed 17981204]).[supplied by OMIM
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