BAIAP2 MaxPab rabbit polyclonal antibody (D01)
产品名称： BAIAP2 MaxPab rabbit polyclonal antibody (D01)
英文名称： BAIAP2 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00010458-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human BAIAP2 protein.
- Immunogen:
- BAIAP2 (NP_059345.1, 1 a.a. ~ 552 a.a) full-length human protein.
- Sequence:
- MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRCDLSAQGPEGREHGDGSARTLAGR
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of BAIAP2 expression in transfected 293T cell line (H00010458-T02) by BAIAP2 MaxPab polyclonal antibody.
Lane 1: BAIAP2 transfected lysate(60.9 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of BAIAP2 transfected lysate using anti-BAIAP2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with BAIAP2 purified MaxPab mouse polyclonal antibody (B01P) (H00010458-B01P).
- Protocol Download
- Entrez GeneID:
- 10458
- GeneBank Accession#:
- NM_017451.1
- Protein Accession#:
- NP_059345.1
- Gene Name:
- BAIAP2
- Gene Alias:
- BAP2,IRSP53
- Gene Description:
- BAI1-associated protein 2
- Omim ID:
- 605475
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
- Other Designations:
- insulin receptor substrate p53
- Gene Pathway