NPHS2 purified MaxPab mouse polyclonal antibody (B01P)
产品名称: NPHS2 purified MaxPab mouse polyclonal antibody (B01P)
英文名称: NPHS2 purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00007827-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human NPHS2 protein.
- Immunogen:
- NPHS2 (AAH29141.1, 1 a.a. ~ 315 a.a) full-length human protein.
- Sequence:
- MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
- Download
- Applications
- Western Blot (Tissue lysate)
- NPHS2 MaxPab polyclonal antibody. Western Blot analysis of NPHS2 expression in human placenta.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of NPHS2 expression in transfected 293T cell line (H00007827-T01) by NPHS2 MaxPab polyclonal antibody.
Lane 1: NPHS2 transfected lysate(34.65 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 7827
- GeneBank Accession#:
- BC029141
- Protein Accession#:
- AAH29141.1
- Gene Name:
- NPHS2
- Gene Alias:
- PDCN,SRN1
- Gene Description:
- nephrosis 2, idiopathic, steroid-resistant (podocin)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000033186,podocin
- Related Disease
- Albuminuria
- Alport syndrome
- Atherosclerosis
- Cardiovascular Diseases
- Chronic Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Eye Diseases
- Genetic Predisposition to Disease
- Glomerulonephritis, IGA
- Glomerulosclerosis, Focal Segmental
- Hypertension
- Kidney Diseases
- Kidney Failure, Chronic
- Nephritis
- Nephrosis, Lipoid